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Diabetes mellitis predisposes patients to numerous systemic ailments with increased morbidity and mortality. Does it increase colorectal cancer too?
This question was recently answered by Dr. Limburg and colleagues from the Mayo Clinic College of Medicine in Rochester, Minnesota in their report published in the American Journal of Gastroenterology (August 2006).
Is It Leaky Gut or Leaky Gut Syndrome?
These investigators identified a cohort of diabetic (type 2) Rochester residents (997 men and 978 women) between 1970 and 1994. Over this period, they found that colorectal cancer occurred in 51 cases in the diabetic group as opposed to 36.8 expected cases. This risk was greater in men and among smokers. It remains to be determined how and/or if the metabolic factors involved in glucose metabolism are involved in the cancer process.
Take home lesson: Quit smoking. Maintain diabetes under control with the help of your physician.
