Facebook Dr. Anil Home page AutismItsGutStupid
Wall Street Journal Best Seller Dr. M's Seven-X Plan for Digestive Health
Abnormalities of metabolism involving vitamin B12 and folic acid have been implicated as one of the causative factors for autism spectrum disorders.
Testing of potentially toxic homocysteine levels is commonly used by neurologists and psychiatrists as part of work-up of a variety of brain disorders and cognitive dysfunction including dementia. Such testing is especially undertaken when vitamin B12 levels are within "normal" range.
Is It Leaky Gut or Leaky Gut Syndrome?
Multiple Western studies have demonstrated high levels of homocysteine in autism spectrum disorders. While autism is more common in th West, a similar correlation in Eastern societies also would lend support to hypothesis that folate-B12-homocyteine metabolism reactions may play a key role in environmental factors in autism.
Background on Homocysteine and B12, Folic acid: Dietary amino acid methionine is converted to homocysteine in body. This potentially toxic homocysteine may be converted to cystien or even back to methionine by enzymes involving vitamin B12 and folic acid.
- A potential deficiency of these vitamins can cause an abnormal levels of homocysteine in the body.
- Some data suggests that supplemention with vitamins lowers homocysteine levels
- There are reportsthat kids with autism respond to the vitamin supplements
Wall Street Journal Best Seller Dr. M's Seven-X Plan for Digestive Health
Potential causes of low vitamin B6, B12 and folic acid levels in body:
- Dietary deficiency
- Selective food choices
- Gastrointestinal dysfunction including mal-digestion and malabsorption of nutrients. Digestive enzyme supplements have been beneficial in some studies.
FREE at Barnes & Noble: Doctor's Guide to Milk and Your Health: The Good, The Bad or The Slow Poison
Autism Homocysteine B12 Study Overview: Dr. Ali and colleaagues from the Sultan Qaboos University in Oman and NorthEastern University in Boston, MA conducted a case control study comparing fasting homocysteine, folic acid and vitamin B12 levels in 40 kids with autism and 40 healthy controls.
Autism Homocysteine B12 Study: The investigators compared homocysteine, folic acid and vitamin B12 levels in autism kids and age-gender matched controls. Diagnosis of autism was made based on the American Psychiatric Association (DSMIV) criteria. Clinical DSM IV criteria was confirmed using Childhood Autism Rating Scale (CARS).
Results of Autism Homocysteine B12 Folic Acid Study:
- Homocysteine levels were significantly higher (more than twice the average 20.1 v 9.6) in kids with autism as compared to healthy controls.
- Mean vitamin B12 levels were significantly lower in autism as compared to controls (191 v 289 pg/ml)
- Average folic acid levels were several fold lower in autism as compared to controls (1.8 v 6.1 mcg/L )
Conclusions of Autism Homocysteine B12 Folic Acid Study:
- Elevated homocysteine is biomarker and may used for early testing for autism
- Elevated homocysteine may be involved as a causative factor and/or involved in progression of the disease.
Is It Leaky Gut or Leaky Gut Syndrome?
FREE at Barnes & Noble: Doctor's Guide to Milk and Your Health: The Good, The Bad or The Slow Poison
Wall Street Journal Best Seller Dr. M's Seven-X Plan for Digestive Health
More topics of interest:
Is It Leaky Gut or Leaky Gut Syndrome?
Facebook Dr. Anil Home page AutismItsGutStupid
Wall Street Journal Best Seller Dr. M's Seven-X Plan for Digestive Health
| Kid getting frequent infections? Probiotics may help | Botox is not just for wrinkles on face: Useful for anal fissures? |
| Bacteria inside gut are a microuniverse with health and disease implications. | Treatment of internet sex addiction |
|
Causes and treatment of hiccups
|
Glutamine and immune system |
| Natural aphrodisiac foods | Diet as riskfor Crohn’s disease |
| Cancer risk of artificial sweeteners | Cognitive behavioral therapy CBT for Irritable Bowel Syndrome |
| GERD acupuncture treatment |
Placebo pain relievers and price
|
Is It Leaky Gut or Leaky Gut Syndrome?
Facebook Dr. Anil Home page AutismItsGutStupid
Wall Street Journal Best Seller Dr. M's Seven-X Plan for Digestive Health
Comments