The effect of iron supplementation on intestinal permeability was examined as part of a randomized iron plus multi-micronutrient (without iron) supplementation trial in Zambian children (n=153; mean age 10.2 years) over period of ten months.
Iron supplementation resulted in a higher lactulose to mannitol ratio indicating increased intestinal permeability as compared to controls whereas there was no impact of no effect of multi-micronutrient supplementation. The authors (Nchito and colleagues) speculated that this could in part explain the deleterious health effects of iron documented in some studies.
Preponderance of evidence suggests that unselected addition of multiple micronutrients to iron supplementation in children with iron deficiency anemia only marginally improve response as assessed by hemoglobin; on the other hand, these additional unselected micronutrients may have an adverse impact of their own and the routine use for treatment of iron deficiency anemia may not be justified.
Bottom line is everything should be in moderation; iron can be toxic; you should take iron if you need it, but be sure that you do actually need it in consultation with your physician.
Are you taking iron supplements? Have your iron levels been checked on periodic basis? Please share your thoughts.
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Too much of everything is bad for us. Excessive iron like for example can have the short time effect of leading to constipation.
Posted by: sisu vitamins | July 19, 2011 at 09:18 PM
Lack of iron may lead to unusual tiredness, shortness of breath, a decrease in physical performance, and learning problems in children and adults, and may increase your chance of getting an infection.
Posted by: liquid iron supplement | April 13, 2011 at 12:44 AM