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Vitamin D deficiency is an exploding epidemic. Besides bone disorders like osteoporosis, vitamin D has been associated a with a variety of ailments including skin disorders, infection and cancer. Multiple reports document that illnesess as common as asthma and COPD may be linked as well.
Increased airway smooth muscle mass plays a critical role in chronic asthmatic airway. Clifford and Knox argue that the inhibition of its proliferation of this airway smooth muscle mass may be a associated with vitamin D related metabolic pathways. Vitamin D may thus be a potential treatment for airway remodelling in asthma.
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