Data suggests the efficacy of selenium for prevention of colon cancer in humans. The source of selenium may be an important factor as well since selenium in broccoli does not accumulate in the body as fast as other forms of Selenium.
Ine one experiment, rats (n = 45) were assigned to torula yeast-based diets supplemented with the following: 1) no Se; 2) selenium as selenate; 3) selenized broccoli. In another experiment, rats were assigned to same basal diet supplemented with the following: 1) no added Se; 2) selenium as selenite; 3) selenium as as selenite + low Selenium broccoli; and 4) selenized broccoli.
Rats were also fed a chemical carcinogen or control vehicle. Supranutritional amounts of selenium ingested as high selenium broccoli significantly reduced the incidence of preneoplastic aberrant crypts and aberrant crypt foci as compared to other groups.This was despite controlling for the presence or absence of broccoli and for the total amount of selenium ingested.
The authors concluded that the decrease in preneoplastic lesions was due to selenium in high selenium broccoli and not a result of broccoli alone or selenium alone.
This suggests that selenium dervived from high selenium broccoli is metabolized such that it diverts much of the selenium into a pool that protects against against colon cancer.
Do you prefer taking supplements as opposed to fresh vegetables and fruit? Please share your thoughts on this article in context of your dietery habits.


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